Glutamate-5-semialdehyde

Glutamate-5-semialdehyde
Names
IUPAC name
(2S)-2-Amino-5-oxopentanoic acid
Other names
L-Glutamate gamma-semialdehyde; gamma-Glutamyl semialdehyde
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
DrugBank
KEGG
UNII
  • InChI=1S/C5H9NO3/c6-4(5(8)9)2-1-3-7/h3-4H,1-2,6H2,(H,8,9)/t4-/m0/s1
    Key: KABXUUFDPUOJMW-BYPYZUCNSA-N
  • C(C[C@@H](C(=O)O)N)C=O
Properties
C5H9NO3
Molar mass 131.131 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Glutamate-5-semialdehyde is a non-proteinogenic amino acid involved in both the biosynthesis and degradation of proline and arginine (via ornithine), as well as in the biosynthesis of antibiotics, such as carbapenems. It is synthesized by the reduction of glutamyl-5-phosphate by glutamate-5-semialdehyde dehydrogenase.

Reduction of glutamic acid semialdehyde with sodium borohydride gives hydroxyaminovaleric acid.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.