HSPA13

HSPA13
Identifiers
Aliases	HSPA13, STCH, heat shock protein family A (Hsp70) member 13
External IDs	OMIM: 601100; MGI: 1309463; HomoloGene: 5062; GeneCards: HSPA13; OMA:HSPA13 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	14,383,484 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	75,563,992 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; cartilage tissue; ; islet of Langerhans; ; ganglionic eminence; ; endothelial cell; ; corpus epididymis; ; retinal pigment epithelium; ; beta cell; ; caput epididymis; ; orbitofrontal cortex;
	Top expressed in
	hand; ; lacrimal gland; ; seminal vesicula; ; superior cervical ganglion; ; otolith organ; ; arcuate nucleus; ; median eminence; ; utricle; ; cumulus cell; ; dermis;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein binding; ATP binding; ATPase activity; heat shock protein binding; protein folding chaperone activity; unfolded protein binding; misfolded protein binding;
Cellular component	extracellular exosome; endoplasmic reticulum; intracellular membrane-bounded organelle; nucleus; cytoplasm; endoplasmic reticulum lumen; membrane; endoplasmic reticulum chaperone complex;
Biological process	response to unfolded protein; ubiquitin-dependent ERAD pathway; endoplasmic reticulum unfolded protein response; cellular response to heat; Unfolded Protein Response; protein refolding; chaperone cofactor-dependent protein refolding;
	Sources:Amigo / QuickGO
Orthologs
	6782
	110920
	ENSG00000155304
	ENSMUSG00000032932
	P48723
	Q8BM72
	NM_006948
	NM_030201
	NP_008879
	NP_084477
	Wikidata
View/Edit Human	View/Edit Mouse

Heat shock 70 kDa protein 13 is a protein that in humans is encoded by the HSPA13 gene.

The protein encoded by this gene is a member of the heat shock protein 70 family and is found associated with endoplasmic reticulum. Members of this protein family play a role in the processing of cytosolic and secretory proteins, as well as in the removal of denatured or incorrectly folded proteins. The encoded protein contains an ATPase domain and has been shown to associate with a ubiquitin-like protein.