Winston-Salem Northern Beltway
| Open segment shown in red; segment under construction in blue; proposed NC 452 in purple | |
| Route information | |
| Maintained by NCDOT | |
| Length | 12.5 mi (20.1 km) | 
| Existed | 2020–present | 
| Component highways | 
 | 
| Major junctions | |
| West end | US 52 near Rural Hall | 
| 
 | |
| East end | US 421 / NC 150 in Kernersville | 
| Location | |
| Country | United States | 
| State | North Carolina | 
| Counties | Forsyth | 
| Highway system | |
The Winston-Salem Northern Beltway is a partially completed freeway loop around the city of Winston-Salem in North Carolina. The western section has been designated as North Carolina Highway 452 (NC 452), which will become I-274 when completed, and the eastern section of the beltway will is designated as North Carolina Highway 74 (NC 74), which will become part of I-74 when completed. The entire route is in Forsyth County.
The beltway would make Winston-Salem the seventh city in North Carolina to have a full or partial Interstate loop; the other six are Asheville (I-240), Charlotte (I-485 and I-277), Raleigh (I-440 and I-540), Wilmington (I-140), Greensboro (I-840), and Fayetteville (I-295).