Ionis Pharmaceuticals

Ionis Pharmaceuticals, Inc.
FormerlyIsis Pharmaceuticals, Inc.
Company typePublic
IndustryBiotechnology
Founded1989 (1989)
FounderStanley T. Crooke
HeadquartersCarlsbad, California, U.S.
Key people
Brett P. Monia (CEO)
Elizabeth L. Hougen (CFO)
Joseph Loscalzo
(chairman of the board)
Productsnusinersen, inotersen, volanesorsen, olezarsen, eplontersen, tofersen
Revenue US$705 million (2024)
US$−270 million (2022)
Total assets US$3 billion (2024)
Total equity US$588 million (2024)
Number of employees
1,069 (2024)
Websiteionispharma.com
Footnotes / references

Ionis Pharmaceuticals, Inc. is a biotechnology company based in Carlsbad, California, that specializes in discovering and developing RNA-targeted therapeutics. The company has three commercially approved medicines: Spinraza (Nusinersen), Tegsedi (Inotersen), and Waylivra (Volanesorsen), and has four drugs in pivotal studies: tominersen for Huntington's disease (together with Roche), tofersen for SOD1-ALS, AKCEA-APO(a)-LRx for cardiovascular disease, and AKCEA-TTR-LRx for all forms of TTR amyloidosis.

The company was named Isis Pharmaceuticals until December 2015.