Levosulpiride
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| Trade names | Dislep, Sulpepta, others |
| Other names | L-Sulpiride; S-(–)-Sulpiride; RV-12309 |
| Routes of administration | Oral |
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| Formula | C15H23N3O4S |
| Molar mass | 341.43 g·mol−1 |
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Levosulpiride, sold under the brand names Dislep and Sulpepta among others, is a dopamine antagonist medication which is used in the treatment of psychotic disorders like schizophrenia, major depressive disorder, nausea and vomiting, and gastroparesis. It is taken by mouth.
It is a selective antagonist of the dopamine D2 receptor and an agonist of the serotonin 5-HT4 receptor. Chemically, it is a benzamide and the (S)-(−)-enantiomer of sulpiride.
Levosulpiride is marketed widely throughout the world, including in Europe, South Korea, Latin America, India, and Pakistan. It is not available in the United States or the United Kingdom.