MFAP2

MFAP2
Identifiers
Aliases	MFAP2, MAGP, MAGP-1, MAGP1, microfibrillar associated protein 2, microfibril associated protein 2
External IDs	OMIM: 156790; MGI: 99559; HomoloGene: 1801; GeneCards: MFAP2; OMA:MFAP2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	16,980,632 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	140,743,295 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; ventricular zone; ; gallbladder; ; canal of the cervix; ; right coronary artery; ; ganglionic eminence; ; placenta; ; Descending thoracic aorta; ; ascending aorta; ; body of uterus;
	Top expressed in
	efferent ductule; ; dermis; ; ventricular zone; ; maxillary prominence; ; external carotid artery; ; internal carotid artery; ; vestibular sensory epithelium; ; hand; ; mandibular prominence; ; umbilical cord;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	extracellular matrix structural constituent;
Cellular component	microfibril; extracellular region; collagen-containing extracellular matrix;
Biological process	embryonic eye morphogenesis; post-embryonic eye morphogenesis; extracellular matrix organization; positive regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
Orthologs
	4237
	17150
	ENSG00000117122
	ENSMUSG00000060572
	P55001
	P55002; Q99PM0
	NM_001135247; NM_001135248; NM_002403; NM_017459
	NM_001161799; NM_008546; NM_001369292
	NP_001128719; NP_001128720; NP_002394; NP_059453
	NP_001155271; NP_032572; NP_001356221
	Wikidata
View/Edit Human	View/Edit Mouse

Microfibrillar-associated protein 2 is a protein that in humans is encoded by the MFAP2 gene.

Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. This gene encodes two transcripts with two alternatively spliced 5' untranslated exons. These two transcripts contain the same eight coding exons, and therefore, encode the same protein.