MYO10

MYO10
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMYO10, myosin X, MyoX
External IDsOMIM: 601481; MGI: 107716; HomoloGene: 36328; GeneCards: MYO10; OMA:MYO10 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

4651

17909

Ensembl

ENSG00000145555

ENSMUSG00000022272

UniProt

Q9HD67

F8VQB6

RefSeq (mRNA)

NM_012334

NM_019472
NM_001353141
NM_001353142

RefSeq (protein)

NP_036466

NP_062345
NP_001340070
NP_001340071

Location (UCSC)Chr 5: 16.66 – 16.94 MbChr 15: 25.62 – 25.81 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Myosin X, also known as MYO10, is a protein that in humans is encoded by the MYO10 gene.

Myo10 is an actin-based motor protein that can localize to the tips of the finger-like cellular protrusions known as filopodia. Myo10 is broadly expressed in mammalian tissues, although at relatively low levels. Studies with knockout mice demonstrate that Myo10 has important functions in embryonic processes such as neural tube closure and eye development. Myo10 also has important functions in cancer invasion and growth.

Myo10 should not be confused with Myh10, which encodes the heavy chain of the class II myosin known as non-muscle myosin 2b.