MYO1E

MYO1E
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XMF
Identifiers
Aliases	MYO1E, FSGS6, HuncM-IC, MYO1C, myosin IE
External IDs	OMIM: 601479; MGI: 106621; HomoloGene: 55864; GeneCards: MYO1E; OMA:MYO1E - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	59,372,871 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	70,307,048 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; sural nerve; ; gallbladder; ; tibial arteries; ; rectum; ; stromal cell of endometrium; ; skin of leg; ; Descending thoracic aorta; ; mucosa of transverse colon; ; ascending aorta;
	Top expressed in
	lumbar spinal ganglion; ; mesenteric lymph nodes; ; calvaria; ; left colon; ; lip; ; cumulus cell; ; tail of embryo; ; duodenum; ; epithelium of stomach; ; lacrimal gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; calmodulin binding; actin filament binding; microfilament motor activity; protein binding; phosphatidylinositol binding; actin binding; cytoskeletal motor activity; ATP binding; lipid binding;
Cellular component	cytoplasm; cell-cell junction; clathrin-coated endocytic vesicle; adherens junction; cell junction; brush border; actin cytoskeleton; extracellular exosome; cytoskeleton; cytoplasmic vesicle; clathrin-coated vesicle; myosin complex;
Biological process	hemopoiesis; endocytosis; glomerular visceral epithelial cell development; glomerular basement membrane development; kidney development; post-embryonic hemopoiesis; in utero embryonic development; actin filament-based movement; vasculogenesis; nitrogen compound metabolic process; glomerular filtration; platelet-derived growth factor receptor signaling pathway; metabolism;
	Sources:Amigo / QuickGO
Orthologs
	4643
	71602
	ENSG00000157483
	ENSMUSG00000032220
	Q12965
	E9Q634
	NM_004998
	NM_181072; NM_025612
	NP_004989
	NP_851417
	Wikidata
View/Edit Human	View/Edit Mouse

Myosin-Ie (Myo1e) is a protein that in humans is encoded by the MYO1E gene.

Myosin-Ie is a long tailed myosin. It contains an N-terminal motor domain, an IQ motif, a TH1 domain containing a plecstrin homology (PH) domain, a proline rich TH2 domain, and an SH3 domain.

The MYO1E gene was included in several genetic signatures for cancer prognosis.