Macrophage inflammatory protein

chemokine (C-C motif) ligand 3
Human Mip-1α dimer D26A mutant. PDB 1b53. Disulfide bonds highlighted.
Identifiers
SymbolCCL3
Alt. symbolsSCYA3, MIP-1α
NCBI gene6348
HGNC10627
OMIM182283
PDB1B50 More structures
RefSeqNM_002983
UniProtP10147
Other data
LocusChr. 17 q12
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StructuresSwiss-model
DomainsInterPro
chemokine (C-C motif) ligand 4
Human Mip-1β dimer. PDB 1hum. Disulfide bonds highlighted.
Identifiers
SymbolCCL4
Alt. symbolsSCYA4, MIP-1β, LAG1
NCBI gene6351
HGNC10630
OMIM182284
PDB1HUM More structures
RefSeqNM_002984
UniProtP13236
Other data
LocusChr. 17 q21-q23
Search for
StructuresSwiss-model
DomainsInterPro

Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1α and MIP-1β, renamed CCL3 and CCL4 respectively, since 2000. However, other names are sometimes encountered in older literature, such as LD78α, AT 464.1 and GOS19-1 for human CCL3 and AT 744, Act-2, LAG-1, HC21 and G-26 for human CCL4. Other macrophage inflammatory proteins include MIP-2, MIP-3 and MIP-5.

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