NFIX

NFIX
Identifiers
Aliases	NFIX, MRSHSS, NF1A, SOTOS2, nuclear factor I X, NF1-X, NF-I/X, CTF, MALNS
External IDs	OMIM: 164005; MGI: 97311; HomoloGene: 1872; GeneCards: NFIX; OMA:NFIX - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	13,098,796 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	84,800,344 bp
RNA expression pattern
	Top expressed in
	nipple; ; ganglionic eminence; ; inferior ganglion of vagus nerve; ; postcentral gyrus; ; internal globus pallidus; ; ventral tegmental area; ; tendon of biceps brachii; ; buccal mucosa cell; ; cardia; ; urethra;
	Top expressed in
	Rostral migratory stream; ; internal carotid artery; ; external carotid artery; ; ankle; ; utricle; ; tunica media of zone of aorta; ; subiculum; ; ascending aorta; ; lacrimal gland; ; vestibular membrane of cochlear duct;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	intracellular anatomical structure; nucleus;
Biological process	DNA replication; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	4784
	18032
	ENSG00000008441
	ENSMUSG00000001911
	Q14938
	P70257
NM_001271043; NM_001271044; NM_002501; NM_001365902; NM_001365982;
	NM_001365983; NM_001365984; NM_001365985; NM_001378404; NM_001378405
	NM_001081981; NM_001081982; NM_001297601; NM_010906
NP_001257972; NP_001257973; NP_002492; NP_001352831; NP_001352911;
	NP_001352912; NP_001352913; NP_001352914; NP_001365333; NP_001365334
NP_001075450; NP_001075451; NP_001284530; NP_035036; NP_001357981;
	NP_001357982; NP_001357983; NP_001357984; NP_001357985; NP_001357986; NP_001357987; NP_001357988; NP_001357989; NP_001357990; NP_001357991; NP_001357992
	Wikidata
View/Edit Human	View/Edit Mouse

Nuclear factor 1 X-type is a protein that in humans is encoded by the NFIX gene. NFI-X3, a splice variant of NFIX, regulates Glial fibrillary acidic protein and YKL-40 in astrocytes.