NRAP

NRAP
Identifiers
Aliases	NRAP, N-RAP, nebulin related anchoring protein
External IDs	OMIM: 602873; MGI: 1098765; HomoloGene: 4499; GeneCards: NRAP; OMA:NRAP - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	113,664,070 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	56,378,469 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of rectus abdominis; ; muscle of thigh; ; glutes; ; gastrocnemius muscle; ; apex of heart; ; body of tongue; ; Skeletal muscle tissue of biceps brachii; ; triceps brachii muscle; ; thoracic diaphragm; ; ventricle of the heart;
	Top expressed in
	ankle; ; muscle of thigh; ; soleus muscle; ; temporal muscle; ; triceps brachii muscle; ; plantaris muscle; ; extensor digitorum longus muscle; ; tibialis anterior muscle; ; medial head of gastrocnemius muscle; ; digastric muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	actin binding; metal ion binding; muscle alpha-actinin binding; protein binding; actin filament binding;
Cellular component	fascia adherens; muscle tendon junction; Z discdkac;
Biological process	biological process; cardiac muscle thin filament assembly;
	Sources:Amigo / QuickGO
Orthologs
	4892
	18175
	ENSG00000197893
	ENSMUSG00000049134
	Q86VF7
	Q80XB4
	NM_001261463; NM_006175; NM_198060; NM_001322945
	NM_001286552; NM_008733; NM_198059
	NP_001248392; NP_001309874; NP_006166; NP_932326
NP_001273481; NP_032759; NP_932307; NP_001390105; NP_001390107;
	NP_001390109; NP_001390113; NP_001390114; NP_001390115; NP_001390116; NP_001390117; NP_001390119; NP_001390120; NP_001390121; NP_001390122; NP_001390123; NP_001390124; NP_001390125
	Wikidata
View/Edit Human	View/Edit Mouse

Nebulin-related-anchoring protein (N-RAP) is a protein that in humans is encoded by the NRAP gene. N-RAP is a muscle-specific isoform belonging to the nebulin family of proteins. This family is composed of 5 members: N-RAP, nebulin, nebulette, LASP-1 and LASP-2. N-RAP is involved in both myofibrillar myogenesis during development and cell-cell connections in mature muscle.