Newfoundland and Labrador Route 221
| Burin Road | ||||
| Route information | ||||
| Maintained by Newfoundland and Labrador Department of Transportation and Infrastructure | ||||
| Length | 15.9 km (9.9 mi) | |||
| Major junctions | ||||
| West end | Route 220 in Burin | |||
| East end | Anile’s Cove Road / Dimmer’s Lane in Fox Cove-Mortier | |||
| Location | ||||
| Country | Canada | |||
| Province | Newfoundland and Labrador | |||
| Highway system | ||||
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| 
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Route 221, also known as Burin Road, is a 15.9-kilometre-long (9.9 mi) east–west highway on the Burin Peninsula of the island of Newfoundland in the province of Newfoundland and Labrador. It connects Fox Cove-Mortier with Port au Bras, Burin, and Route 220 (Burin Peninsula Highway).