OSBPL5

OSBPL5
Identifiers
Aliases	OSBPL5, OBPH1, ORP5, oxysterol binding protein like 5
External IDs	OMIM: 606733; MGI: 1930265; HomoloGene: 98024; GeneCards: OSBPL5; OMA:OSBPL5 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	3,166,739 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	143,310,722 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; tendon of biceps brachii; ; canal of the cervix; ; granulocyte; ; sural nerve; ; ectocervix; ; popliteal artery; ; tibial arteries; ; thoracic aorta; ; Descending thoracic aorta;
	Top expressed in
	Ileal epithelium; ; corneal stroma; ; sciatic nerve; ; lip; ; ankle joint; ; decidua; ; superior surface of tongue; ; plantaris muscle; ; cardiac muscle tissue of left ventricle; ; esophagus;
	More reference expression data
	n/a
Gene ontology
Molecular function	cholesterol binding; phosphatidylinositol-4-phosphate binding; oxysterol binding; phosphatidylserine binding; lipid binding; phospholipid transporter activity; sterol transporter activity; sterol binding;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; cytosol; intracellular membrane-bounded organelle; endoplasmic reticulum-plasma membrane contact site;
Biological process	phospholipid transport; cholesterol transport; lipid transport; cholesterol metabolic process; Golgi to plasma membrane transport; phosphatidylserine acyl-chain remodeling; transport;
	Sources:Amigo / QuickGO
Orthologs
	114879
	79196
	ENSG00000021762
	ENSMUSG00000037606
	Q9H0X9
	Q9ER64
	NM_001144063; NM_020896; NM_145638
	NM_001199227; NM_024289; NM_001384163
	NP_001137535; NP_065947; NP_663613
	NP_001186156; NP_077251; NP_001371092
	Wikidata
View/Edit Human	View/Edit Mouse

Oxysterol-binding protein-related protein 5 is a protein that in humans is encoded by the OSBPL5 gene.

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Transcript variants encoding different isoforms have been identified.