Ornithine aminotransferase
| ornithine aminotransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
OAT + PLP, Human | |||||||||
| Identifiers | |||||||||
| EC no. | 2.6.1.13 | ||||||||
| CAS no. | 9030-42-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
| ornithine aminotransferase | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | OAT | ||||||
| NCBI gene | 4942 | ||||||
| HGNC | 8091 | ||||||
| OMIM | 258870 | ||||||
| RefSeq | NM_000274 | ||||||
| UniProt | P04181 | ||||||
| Other data | |||||||
| EC number | 2.6.1.13 | ||||||
| Locus | Chr. 10 q26 | ||||||
| |||||||
Ornithine aminotransferase (OAT) is an enzyme which is encoded in human by the OAT gene located on chromosome 10.
The OAT involved in the ultimate formation of the non-essential amino acid proline from the amino acid ornithine. Ornithine aminotransferase forms the initial intermediate in this process. It catalyzes the reverse reaction as well, and is therefore essential in creating ornithine from the starting substrate proline.