| Ottoman–Safavid wars | 
|---|
| Part of Ottoman–Persian Wars | 
 Safavid campaign of Selim I and Mehmed Pasha (1515–1517) | 
| Date | 1505–1517 | 
|---|
 | Location |  | 
|---|
 | Result | 
Ottoman victory | 
|---|
 Territorial changes | 
Eastern Anatolia and Northern Iraq annexed by Ottomans | 
|---|
 
  | 
| Belligerents | 
|---|
| 
  Ottoman Empire Supported by: 
 | 
  Safavid Iran Supported by: 
 | 
| Commanders and leaders | 
|---|
 Beyazid II #  Selim I
 
-  Mustafa Pasha
  Şehzade Korkut   Serasker Hasan Bey †  Murad Pasha †  Hadım Ali Pasha †  Karagöz Ahmet Pasha   Haydar Pasha †  Kâtip Ali Pasha †  Cündî Kemal Bey †  Haydar Bey †  Şehzade Murad    Hadım Sinan Pasha  Yularkıstı Sinan Pasha †  Hasan Pasha †  Malkoçoğlu Turali Bey †  Malkoçoğlu Ali Bey †  Malkoçoğlu Bali Bey †  Bıyıklı Mehmed Pasha  Yiğit Ahmet  Cemşid Bey  Idris Bitlisi  Pir Hüseyin Bey  Şadi Pasha   Çerkes Hüseyin Bey †  Karaçinoğlu Ahmet Bey  Mevahib Çelebi  Seyyid Ahmed Bey  Bedir Bey  Mehmed Çelebi †  Deli Husrev Pasha   Karaçin Ahmed Bey  Halil Eyyubi  Atak Ahmed Beg  Çavuş Ahmed Beg  Mirza Mehmed Beg †  Kızıl Ahmet Beg †  
  | 
 Ismail I (WIA)
  | 
| Casualties and losses | 
|---|
| 
 Heavy 
-  50,000 killed in Anatolia (including civilians)
 
  | 
 Heavy 
-  40,000–200,000 Qizilbashs massacred (including civilians, exaggerated)
 
  | 
 | 
|---|
- Ottoman–Safavid Wars
  
- Campaigns of Nader Shah
  
- Subsequent conflicts
  
  | 
 
The Ottoman–Persian wars (1505–1517) were a series of military conflicts fought between the Ottoman Empire and the Safavid dynasty of Iran during the reign of Sultan Bayezid II and his son Selim I. Sparked by sectarian and territorial rivalries, the wars culminated in major Ottoman victories, including the pivotal Battle of Chaldiran (1514) and the subsequent conquest of Eastern Anatolia and northern Mesopotamia. These campaigns marked the beginning of a long-standing Ottoman–Persian rivalry that would last until 1918