PARVA

PARVA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2K2R, 2VZC, 2VZD, 2VZG, 2VZI, 3KMU, 3KMW, 3REP
Identifiers
Aliases	PARVA, CH-ILKBP, MXRA2, parvin alpha
External IDs	OMIM: 608120; MGI: 1931144; HomoloGene: 10077; GeneCards: PARVA; OMA:PARVA - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	12,535,356 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	112,190,899 bp
RNA expression pattern
	Top expressed in
	smooth muscle tissue; ; stromal cell of endometrium; ; epithelium of colon; ; myometrium; ; muscle layer of sigmoid colon; ; saphenous vein; ; gastric mucosa; ; glomerulus; ; tail of epididymis; ; metanephric glomerulus;
	Top expressed in
	superior cervical ganglion; ; sciatic nerve; ; umbilical cord; ; uterus; ; carotid body; ; Epithelium of choroid plexus; ; external carotid artery; ; olfactory epithelium; ; right lung lobe; ; tunica media of zone of aorta;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; actin binding; cadherin binding;
Cellular component	cytoplasm; cytosol; membrane; plasma membrane; cell junction; Z discdkac; cytoskeleton; focal adhesion; actin cytoskeleton; nucleus; lamellipodium;
Biological process	actin cytoskeleton reorganization; cilium assembly; smooth muscle cell chemotaxis; heterotypic cell-cell adhesion; sprouting angiogenesis; outflow tract septum morphogenesis; establishment or maintenance of cell polarity; chemotaxis; actin-mediated cell contraction; cell adhesion; cell projection organization; angiogenesis; regulation of cell shape; substrate adhesion-dependent cell spreading; cell projection assembly;
	Sources:Amigo / QuickGO
Orthologs
	55742
	57342
	ENSG00000197702
	ENSMUSG00000030770
	Q9NVD7
	Q9EPC1
	NM_018222
	NM_020606
	NP_060692
	NP_065631
	Wikidata
View/Edit Human	View/Edit Mouse

Alpha-parvin is a protein that in humans is encoded by the PARVA gene.

Members of the parvin family, including PARVA, PARVB and PARVG, are actin-binding proteins associated with focal contacts.[supplied by OMIM]