PARVB

PARVB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4EDL, 4EDM, 4EDN
Identifiers
Aliases	PARVB, CGI-56, parvin beta
External IDs	OMIM: 608121; MGI: 2153063; HomoloGene: 8342; GeneCards: PARVB; OMA:PARVB - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	44,172,939 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	84,199,889 bp
RNA expression pattern
	Top expressed in
	muscle of thigh; ; gastrocnemius muscle; ; apex of heart; ; monocyte; ; left ventricle; ; right auricle of heart; ; islet of Langerhans; ; right lung; ; right adrenal gland; ; upper lobe of left lung;
	Top expressed in
	blood; ; lumbar spinal ganglion; ; muscle of thigh; ; molar; ; right lobe of liver; ; extraocular muscle; ; soleus muscle; ; digastric muscle; ; atrium; ; yolk sac;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	actin binding; protein binding;
Cellular component	cytoplasm; cytosol; cell junction; plasma membrane; cell projection; sarcomere; Z discdkac; cytoskeleton; membrane; focal adhesion; lamellipodium; actin cytoskeleton;
Biological process	actin cytoskeleton reorganization; cell adhesion; cell projection assembly; lamellipodium assembly; establishment or maintenance of cell polarity regulating cell shape; establishment or maintenance of cell polarity; substrate adhesion-dependent cell spreading;
	Sources:Amigo / QuickGO
Orthologs
	29780
	170736
	ENSG00000188677
	ENSMUSG00000022438
	Q9HBI1
	Q9ES46
	NM_001003828; NM_001243385; NM_001243386; NM_013327
	NM_133167
	NP_001003828; NP_001230314; NP_001230315; NP_037459
	NP_573395
	Wikidata
View/Edit Human	View/Edit Mouse

Beta-parvin is a protein that in humans is encoded by the PARVB gene.

Members of the parvin family, including PARVB, PARVA and PARVG, are actin-binding proteins associated with focal contacts.[supplied by OMIM]