PKNOX1

PKNOX1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X2N
Identifiers
Aliases	PKNOX1, PREP1, pkonx1c, PBX/knotted 1 homeobox 1
External IDs	OMIM: 602100; MGI: 1201409; HomoloGene: 3363; GeneCards: PKNOX1; OMA:PKNOX1 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	43,033,931 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	31,826,667 bp
RNA expression pattern
	Top expressed in
	gonad; ; right lobe of thyroid gland; ; testicle; ; left testis; ; right testis; ; left lobe of thyroid gland; ; ganglionic eminence; ; ventricular zone; ; sural nerve; ; stromal cell of endometrium;
	Top expressed in
	Rostral migratory stream; ; granulocyte; ; vas deferens; ; thymus; ; internal carotid artery; ; efferent ductule; ; spermatocyte; ; human fetus; ; blood; ; external carotid artery;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; sequence-specific DNA binding; DNA binding; protein heterodimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding;
Cellular component	cytoplasm; nucleus; transcription regulator complex; cytosol;
Biological process	erythrocyte differentiation; regulation of transcription by RNA polymerase II; camera-type eye development; T cell differentiation; regulation of transcription, DNA-templated; angiogenesis; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; hemopoiesis;
	Sources:Amigo / QuickGO
Orthologs
	5316
	18771
	ENSG00000160199
	ENSMUSG00000006705
	P55347; Q96I87
	O70477
	NM_001286258; NM_004571; NM_001320694; NM_197976
	NM_016670
NP_001273187; NP_001307623; NP_004562; NP_001273187.1; NP_004562.2;
	NP_001307623.1
	NP_057879
	Wikidata
View/Edit Human	View/Edit Mouse

PBX/Knotted 1 Homeobox 1 (PKNOX1) is a protein that in humans is encoded by the PKNOX1 gene.

An important paralog of this gene is PKNOX2.