PSB-SB-1202

PSB-SB-1202
Identifiers
	IUPAC name 7-pentyl-5-methoxy-3-(2-methoxybenzyl)-2H-chromen-2-one;
CAS Number	1399049-60-5;
PubChem CID	70677953;
ChemSpider	28668367;
UNII	429P6KRK5A;
CompTox Dashboard (EPA)	DTXSID101045359 ;
Chemical and physical data
Formula	C23H26O4
Molar mass	366.457 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C1C(CC2=C(OC)C=CC=C2)=CC3=C(C=C(CCCCC)C=C3OC)O1;
	InChI InChI=1S/C23H26O4/c1-4-5-6-9-16-12-21(26-3)19-15-18(23(24)27-22(19)13-16)14-17-10-7-8-11-20(17)25-2/h7-8,10-13,15H,4-6,9,14H2,1-3H3; Key:VZYCAUIYIZSPQY-UHFFFAOYSA-N;

PSB-SB-1202 is a coumarin derivative which is an agonist at the cannabinoid receptors CB₁ and CB₂, with a CB₁ Ki of 32nM and a CB₂ Ki of 49nM. It is also a weak antagonist at the related receptor GPR55, with an IC₅₀ of 6350nM, but has no significant affinity for GPR18.

Identifiers

IUPAC name 7-pentyl-5-methoxy-3-(2-methoxybenzyl)-2H-chromen-2-one
CAS Number	1399049-60-5
PubChem CID	70677953
ChemSpider	28668367
UNII	429P6KRK5A
CompTox Dashboard (EPA)	DTXSID101045359
Chemical and physical data
Formula	C₂₃H₂₆O₄
Molar mass	366.457 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C1C(CC2=C(OC)C=CC=C2)=CC3=C(C=C(CCCCC)C=C3OC)O1
InChI InChI=1S/C23H26O4/c1-4-5-6-9-16-12-21(26-3)19-15-18(23(24)27-22(19)13-16)14-17-10-7-8-11-20(17)25-2/h7-8,10-13,15H,4-6,9,14H2,1-3H3 Key:VZYCAUIYIZSPQY-UHFFFAOYSA-N