Phosphoenolpyruvate carboxykinase
| Phosphoenolpyruvate carboxykinase | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
PDB rendering based on 1khb. | |||||||||||
| Identifiers | |||||||||||
| Symbol | PEPCK | ||||||||||
| Pfam | PF00821 | ||||||||||
| InterPro | IPR008209 | ||||||||||
| PROSITE | PDOC00421 | ||||||||||
| SCOP2 | 1khf / SCOPe / SUPFAM | ||||||||||
| |||||||||||
| phosphoenolpyruvate carboxykinase 1 (soluble) | |
|---|---|
Phosphoenolpyruvate carboxykinase (GTP, cytosolic) monomer, Human | |
| Identifiers | |
| Symbol | PCK1 |
| Alt. symbols | PEPCK-C |
| NCBI gene | 5105 |
| HGNC | 8724 |
| OMIM | 261680 |
| RefSeq | NM_002591 |
| Other data | |
| EC number | 4.1.1.32 |
| Locus | Chr. 20 q13.31 |
| phosphoenolpyruvate carboxykinase 2 (mitochondrial) | |
|---|---|
| Identifiers | |
| Symbol | PCK2 |
| Alt. symbols | PEPCK-M, PEPCK2 |
| NCBI gene | 5106 |
| HGNC | 8725 |
| OMIM | 261650 |
| RefSeq | NM_001018073 |
| Other data | |
| EC number | 4.1.1.32 |
| Locus | Chr. 14 q12 |
Phosphoenolpyruvate carboxykinase (EC 4.1.1.32, PEPCK) is an enzyme in the lyase family used in the metabolic pathway of gluconeogenesis. It converts oxaloacetate into phosphoenolpyruvate and carbon dioxide.
It is found in two forms, cytosolic and mitochondrial.