RHOBTB2

RHOBTB2
Identifiers
Aliases	RHOBTB2, DBC2, Rho related BTB domain containing 2, EIEE64, p83, DEE64
External IDs	OMIM: 607352; MGI: 2180557; HomoloGene: 22873; GeneCards: RHOBTB2; OMA:RHOBTB2 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	23,020,509 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	70,043,085 bp
RNA expression pattern
	Top expressed in
	upper lobe of left lung; ; right frontal lobe; ; prefrontal cortex; ; caudate nucleus; ; putamen; ; dorsolateral prefrontal cortex; ; right lung; ; Brodmann area 9; ; cingulate gyrus; ; anterior cingulate cortex;
	Top expressed in
	retinal pigment epithelium; ; superior frontal gyrus; ; olfactory tubercle; ; primary visual cortex; ; primary motor cortex; ; dentate gyrus of hippocampal formation granule cell; ; piriform cortex; ; lens; ; superior colliculus; ; otic vesicle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; GTPase activity; protein kinase binding;
Cellular component	cytosol; plasma membrane; intracellular anatomical structure; cytoplasm; cytoskeleton; cell projection;
Biological process	regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; cell morphogenesis; actin filament organization; Rho protein signal transduction; cell migration; actin cytoskeleton organization; positive regulation of actin filament polymerization; actin cytoskeleton reorganization; engulfment of apoptotic cell;
	Sources:Amigo / QuickGO
Orthologs
	23221
	246710
	ENSG00000008853
	ENSMUSG00000022075
	Q9BYZ6
	Q91V93
	NM_001160036; NM_001160037; NM_015178; NM_001374791
	NM_153514
	NP_001153508; NP_001153509; NP_055993; NP_001361720
	NP_705734
	Wikidata
View/Edit Human	View/Edit Mouse

Rho-related BTB domain-containing protein 2 is a protein that in humans is encoded by the RHOBTB2 gene.

RHOBTB2 is a member of the evolutionarily-conserved RhoBTB subfamily of Rho GTPases. For background information on RhoBTBs, see RHOBTB1 (MIM 607351).[supplied by OMIM]