RNF24

RNF24
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EP4
Identifiers
Aliases	RNF24, G1L, ring finger protein 24
External IDs	OMIM: 612489; MGI: 1261771; HomoloGene: 5223; GeneCards: RNF24; OMA:RNF24 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	4,015,558 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	131,194,812 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; blood; ; pericardium; ; cartilage tissue; ; nipple; ; renal medulla; ; stromal cell of endometrium; ; trigeminal ganglion; ; endothelial cell; ; Descending thoracic aorta;
	Top expressed in
	zygote; ; secondary oocyte; ; otolith organ; ; utricle; ; human kidney; ; seminiferous tubule; ; ganglionic eminence; ; hand; ; right kidney; ; proximal tubule;
	More reference expression data
	n/a
Gene ontology
Molecular function	zinc ion binding; protein binding; ubiquitin protein ligase activity; metal ion binding;
Cellular component	integral component of membrane; Golgi membrane; membrane; Golgi apparatus; endomembrane system;
Biological process	protein polyubiquitination; proteasome-mediated ubiquitin-dependent protein catabolic process; protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	11237
	51902
	ENSG00000101236
	ENSMUSG00000048911
	Q9Y225
	Q8BGI1
	NM_001134337; NM_001134338; NM_007219; NM_001321749; NM_016502
	NM_178607
	NP_001127809; NP_001127810; NP_001308678; NP_009150
	NP_848722
	Wikidata
View/Edit Human	View/Edit Mouse

Ring finger protein 24 is a protein that in humans is encoded by the RNF24 gene.

RNF24 binds TRPC6 (603652) and other transient receptor potential cation channel (TRPC) family members and is involved in regulation of intracellular trafficking of TRPCs. In addition, RNF24 contains similarity to the Drosophila goliath protein and thus may function as a transcription factor.