Sacsin

SACS
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1IUR, 3O10
Identifiers
Aliases	SACS, ARDNAJC29, PPP1R138, SPAX6, sacsin molecular chaperone
External IDs	OMIM: 604490; MGI: 1354724; HomoloGene: 8653; GeneCards: SACS; OMA:SACS - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	23,433,763 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	61,478,144 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; middle frontal gyrus; ; frontal pole; ; Brodmann area 10; ; thoracic diaphragm; ; Skeletal muscle tissue of rectus abdominis; ; lateral nuclear group of thalamus; ; middle temporal gyrus; ; biceps brachii; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	pontine nuclei; ; deep cerebellar nuclei; ; medial geniculate nucleus; ; medial dorsal nucleus; ; medial vestibular nucleus; ; lateral geniculate nucleus; ; inferior colliculi; ; dorsal striatum; ; substantia nigra; ; primary motor cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	Hsp70 protein binding; proteasome binding; chaperone binding;
Cellular component	cytoplasm; axon; dendrite; mitochondrion; nucleus; cell body fiber;
Biological process	protein folding; negative regulation of inclusion body assembly;
	Sources:Amigo / QuickGO
Orthologs
	26278
	50720
	ENSG00000151835
	ENSMUSG00000048279
	Q9NZJ4
	Q9JLC8
	NM_001278055; NM_014363; NM_152752
	NM_015788; NM_172809
	NP_001264984; NP_055178
	NP_766397; NP_056603
	Wikidata
View/Edit Human	View/Edit Mouse

Sacsin also known as DnaJ homolog subfamily C member 29 (DNAJC29) is a protein that in humans is encoded by the SACS gene. Sacsin is a Hsp70 co-chaperone.