Nav1.9

SCN11A
Identifiers
Aliases	SCN11A, FEPS3, HSAN7, NAV1.9, NaN, PN5, SCN12A, SNS-2, sodium voltage-gated channel alpha subunit 11
External IDs	OMIM: 604385; MGI: 1345149; HomoloGene: 8041; GeneCards: SCN11A; OMA:SCN11A - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	39,052,157 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	119,654,522 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; spinal ganglia; ; testicle; ; trigeminal ganglion; ; gonad; ; left testis; ; right testis; ; sural nerve; ; spleen; ; ventricular zone;
	Top expressed in
	lumbar spinal ganglion; ; membrana granulosa of ovarian follicle; ; spermatogonium; ; motor neuron; ; embryo; ; saccule; ; pituitary gland; ; Paneth cell; ; lens; ; oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	ion channel activity; sodium channel activity; voltage-gated ion channel activity; voltage-gated sodium channel activity;
Cellular component	voltage-gated sodium channel complex; integral component of membrane; extracellular exosome; membrane; plasma membrane; axon; C-fiber;
Biological process	regulation of ion transmembrane transport; membrane depolarization during action potential; ion transport; sodium ion transmembrane transport; neuronal action potential; transmembrane transport; ion transmembrane transport; sodium ion transport; regulation of postsynaptic membrane potential; regulation of sensory perception of pain; transport;
	Sources:Amigo / QuickGO
Orthologs
	11280
	24046
	ENSG00000168356
	ENSMUSG00000034115
	Q9UI33
	Q9R053
	NM_001287223; NM_014139; NM_001349253
	NM_011887
	NP_054858; NP_001336182
	NP_036017
	Wikidata
View/Edit Human	View/Edit Mouse

Sodium channel, voltage-gated, type XI, alpha subunit also known as SCN11A or Na_v1.9 is a voltage-gated sodium ion channel protein which is encoded by the SCN11A gene on chromosome 3 in humans. Like Na_v1.7 and Na_v1.8, Na_v1.9 plays a role in pain perception. This channel is largely expressed in small-diameter nociceptors of the dorsal root ganglion and trigeminal ganglion neurons, but is also found in intrinsic myenteric neurons.