SNX1

SNX1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2I4K, 4FZS
Identifiers
Aliases	SNX1, HsT17379, VPS5, sorting nexin 1
External IDs	OMIM: 601272; MGI: 1928395; HomoloGene: 99716; GeneCards: SNX1; OMA:SNX1 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	64,146,090 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	66,033,869 bp
RNA expression pattern
	Top expressed in
	right lobe of thyroid gland; ; left lobe of thyroid gland; ; right adrenal gland; ; right adrenal cortex; ; left adrenal gland; ; monocyte; ; upper lobe of left lung; ; ectocervix; ; C1 segment; ; left adrenal cortex;
	Top expressed in
	spermatocyte; ; gastrula; ; spermatid; ; decidua; ; blastocyst; ; saccule; ; morula; ; yolk sac; ; lens; ; ventricular zone;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein homodimerization activity; insulin receptor binding; leptin receptor binding; epidermal growth factor receptor binding; protein binding; phosphatidylinositol binding; identical protein binding; protein heterodimerization activity; transferrin receptor binding; lipid binding; cadherin binding;
Cellular component	cytoplasm; cytosol; Golgi apparatus; cell projection; early endosome membrane; membrane; retromer, tubulation complex; intracellular membrane-bounded organelle; retromer complex; early endosome; endosome membrane; lamellipodium; extrinsic component of membrane; vesicle; lysosome; endosome; protein-containing complex;
Biological process	positive regulation of protein catabolic process; vesicle organization; early endosome to Golgi transport; receptor internalization; endosomal transport; retrograde transport, endosome to Golgi; protein transport; intracellular protein transport; lamellipodium morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	6642
	56440
	ENSG00000028528
	ENSMUSG00000032382
	Q13596
	Q9WV80
	NM_001242933; NM_003099; NM_148955; NM_152826
	NM_019727
	NP_001229862; NP_003090; NP_683758
	NP_062701
	Wikidata
View/Edit Human	View/Edit Mouse

Sorting nexin-1 is a protein that in humans is encoded by the SNX1 gene. The protein encoded by this gene is a sorting nexin. SNX1 is a component of the retromer complex.