SNAG1

SNX18
Identifiers
Aliases	SNX18, SH3PX2, SH3PXD3B, SNAG1, sorting nexin 18
External IDs	MGI: 2137642; HomoloGene: 14164; GeneCards: SNX18; OMA:SNX18 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	54,546,586 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	113,755,100 bp
RNA expression pattern
	Top expressed in
	pancreatic epithelial cell; ; pancreatic ductal cell; ; skin of arm; ; germinal epithelium; ; amniotic fluid; ; palpebral conjunctiva; ; endothelial cell; ; synovial membrane; ; saphenous vein; ; trabecular bone;
	Top expressed in
	cumulus cell; ; medullary collecting duct; ; ascending aorta; ; external carotid artery; ; renal corpuscle; ; aortic valve; ; tunica media of zone of aorta; ; internal carotid artery; ; secondary oocyte; ; sciatic nerve;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; phosphatidylinositol binding; phosphatidylinositol-4,5-bisphosphate binding; lipid binding;
Cellular component	membrane; extrinsic component of cytoplasmic side of plasma membrane; plasma membrane; endosome membrane; extracellular exosome; cytoplasmic vesicle membrane; endomembrane system; clathrin-coated vesicle; cytoplasmic vesicle; endosome;
Biological process	cleavage furrow formation; cell division; endosomal transport; positive regulation of GTPase activity; protein transport; cell cycle; endocytosis; mitotic cytokinesis; mitotic cell cycle; transport;
	Sources:Amigo / QuickGO
Orthologs
	112574
	170625
	ENSG00000178996
	ENSMUSG00000042364
	Q96RF0
	Q91ZR2; Q8C788
	NM_052870; NM_001102575; NM_001145427
	NM_130796
	NP_001096045; NP_001138899; NP_443102
	NP_570614
	Wikidata
View/Edit Human	View/Edit Mouse

Sorting nexin-18 is a protein that in humans is encoded by the SNX18 gene.

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. The specific function of this protein has not been determined.