SUCLG2

SUCLG2
Identifiers
Aliases	SUCLG2, GBETA, succinate-CoA ligase GDP-forming beta subunit, G-SCS, GTPSCS, succinate-CoA ligase GDP-forming subunit beta
External IDs	OMIM: 603922; MGI: 1306824; HomoloGene: 2854; GeneCards: SUCLG2; OMA:SUCLG2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	67,654,612 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	95,695,781 bp
RNA expression pattern
	Top expressed in
	mucosa of colon; ; mucosa of sigmoid colon; ; rectum; ; jejunal mucosa; ; right lobe of liver; ; mucosa of transverse colon; ; duodenum; ; vastus lateralis muscle; ; gastrocnemius muscle; ; Skeletal muscle tissue of rectus abdominis;
	Top expressed in
	right kidney; ; renal cortex; ; proximal tubule; ; human kidney; ; hepatobiliary system; ; liver; ; colon; ; heart; ; ileum; ; stomach;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; succinate-CoA ligase (GDP-forming) activity; ligase activity; catalytic activity; ATP binding; protein heterodimerization activity; GDP binding; metal ion binding; protein binding; magnesium ion binding; succinate-CoA ligase (ADP-forming) activity; succinate-CoA ligase activity;
Cellular component	mitochondrial matrix; plasma membrane; mitochondrion; succinate-CoA ligase complex (GDP-forming); protein-containing complex; succinate-CoA ligase complex;
Biological process	metabolism; tricarboxylic acid cycle; succinate metabolic process; succinyl-CoA metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	8801
	20917
	ENSG00000172340
	ENSMUSG00000061838
	Q96I99
	Q9Z2I8
	NM_001177599; NM_003848
	NM_011507; NM_001326558
	NP_001171070; NP_003839
	NP_001313487; NP_035637
	Wikidata
View/Edit Human	View/Edit Mouse

Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial is an enzyme that in humans is encoded by the SUCLG2 gene on chromosome 3.

This gene encodes a GTP-specific beta subunit of succinyl-CoA synthetase. Succinyl-CoA synthetase catalyzes the reversible reaction involving the formation of succinyl-CoA and succinate. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 5 and 12. [provided by RefSeq, Apr 2010]