South Africa at the 2012 Summer Paralympics

South Africa competed at the 2012 Summer Paralympics in London with a team of 62 athletes and finished 18th on the medal table.

The South African Sports Confederation and Olympic Committee (SASCOC), which is the National Paralympic Committee of South Africa, announced a team of 62 competitors for the 2012 Paralympics on 20 June 2012. The team of 45 men and 17 women were accompanied by 45 managers, coaches and other support staff. SASCOC released the team's schedule on 17 August 2012.

In a surprise announcement in London on 8 September the South African Minister of Sport and Recreation Fikile Mbalula said that Paralympic medal winners and their coaches would receive the same performance bonuses that their Olympic counterparts were promised. The amounts initially promised were significantly lower. The minister said the original plan was discriminatory.