South Carolina Highway 781
| Tinker Creek Road | ||||
| Route information | ||||
| Maintained by SCDOT | ||||
| Length | 3.561 mi (5.731 km) | |||
| Existed | 1940–present | |||
| Major junctions | ||||
| West end | US 278 near the Savannah River Site | |||
| East end | US 78 near White Pond | |||
| Location | ||||
| Country | United States | |||
| State | South Carolina | |||
| Counties | Aiken | |||
| Highway system | ||||
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South Carolina Highway 781 (SC 781) is a 3.561-mile (5.731 km) primary state highway in the U.S. state of South Carolina. It is used as part of a bypass south of Aiken, between Augusta and Williston, in conjunction with U.S. Route 278 (US 278).