TFB2M

TFB2M
Identifiers
Aliases	TFB2M, Hkp1, mtTFB2, transcription factor B2, mitochondrial
External IDs	OMIM: 607055; MGI: 107937; HomoloGene: 7362; GeneCards: TFB2M; OMA:TFB2M - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	246,566,261 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	179,373,832 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; palpebral conjunctiva; ; right adrenal gland; ; right adrenal cortex; ; biceps brachii; ; tibia; ; left adrenal gland; ; right lobe of liver; ; parietal pleura; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	muscle of thigh; ; quadriceps femoris muscle; ; muscle tissue; ; skeletal muscle tissue; ; tail of embryo; ; zygote; ; renal cortex; ; proximal tubule; ; heart; ; epiblast;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	methyltransferase activity; transferase activity; transcription coregulator activity; rRNA methyltransferase activity; rRNA (adenine-N6,N6-)-dimethyltransferase activity; RNA binding;
Cellular component	cell junction; mitochondrial nucleoid; mitochondrial matrix; mitochondrion;
Biological process	positive regulation of transcription, DNA-templated; rRNA processing; methylation; mitochondrion organization; regulation of transcription, DNA-templated; rRNA methylation; transcription, DNA-templated; mitochondrial transcription; transcription initiation from mitochondrial promoter; rRNA modification;
	Sources:Amigo / QuickGO
Orthologs
	64216
	15278
	ENSG00000162851
	ENSMUSG00000026492
	Q9H5Q4
	Q3TL26
	NM_022366
	NM_008249; NM_001331054; NM_001331055
	NP_071761
	NP_001317983; NP_001317984; NP_032275
	Wikidata
View/Edit Human	View/Edit Mouse

Dimethyladenosine transferase 2; transcription factor B2, mitochondrial is an enzyme that in humans is encoded by the TFB2M gene.

This protein is a transcription initiation factor for the mitochondrial RNA polymerase, POLRMT. Its paralog TFB1M can perform a similar function, but only in vitro.