U.S. Route 169 in Missouri
| US 169 highlighted in red | ||||
| Route information | ||||
| Auxiliary route of US 69 | ||||
| Maintained by MoDOT | ||||
| Length | 126.907 mi (204.237 km) | |||
| Major junctions | ||||
| South end | I-70 / US-24 / US-40 / US-169 at Kansas state line | |||
| 
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| North end | US 169 at Iowa state line | |||
| Location | ||||
| Country | United States | |||
| State | Missouri | |||
| Counties | Jackson, Clay, Clinton, Buchanan, Andrew, DeKalb, Gentry, Worth | |||
| Highway system | ||||
| 
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U.S. Route 169 (US 169) is a U.S. Highway that travels from Tulsa, Oklahoma to Virginia, Minnesota. In the state of Missouri, US 169 enters the state from Kansas overlapped with I-70 / US 24 / US 40 at Kansas City and exits the state into Iowa north of Irena.