U.S. Route 301 in South Carolina

U.S. Highway 301
U.S. Highway 301
	US 301 highlighted in red
Route information
	Auxiliary route of US 1
	Maintained by SCDOT
Length	189.704 mi (305.299 km)
Existed	1948–present
Major junctions
South end	US 301 / SR 73 at the Georgia state line near Allendale
	US 278 in Allendale; US 321 in Ulmer; US 21 / US 601 in Orangeburg; I-26 near Orangeburg; US 176 near Elloree; I-95 / US 15 near Summerton; US 521 in Manning; US 378 in Turbeville; US 52 in Effingham; US 76 / SC 327 near Mars Bluff;
North end	I-95 / US 301 / US 501 at the North Carolina state line near Hamer
Location
Country	United States
State	South Carolina
Counties	Allendale, Bamberg, Orangeburg, Clarendon, Florence, Marion, Dillon
Highway system
	United States Numbered Highway System; List; Special; Divided; South Carolina State Highway System; Interstate; US; State; Scenic;

U.S. Route 301 (US 301) is a 189.704-mile (305.299 km) U.S. Highway that travels north–south from the Savannah River southwest of Allendale to Hamer approaching the South of the Border roadside attraction complex.