U.S. Route 45 in Illinois

U.S. Route 45
U.S. Route 45
	US 45 highlighted in red
Route information
	Maintained by IDOT
Length	428.99 mi (690.39 km)
Major junctions
South end	US 45 near Brookport
	I-24 in Metropolis; I-64 near Mill Shoals; US 50 in Flora; I-70 / US 40 in Effingham; I-74 in Urbana; I-57 in Kankakee; US 30 in Frankfort; I-80 in Tinley Park; US 6 in Orland Park; I-55 in Hodgkins;
North end	US 45 near Antioch
Location
Country	United States
State	Illinois
Counties	Massac, Johnson, Williamson, Saline, Gallatin, White, Wayne, Clay, Effingham, Shelby, Cumberland, Coles, Douglas, Champaign, Ford, Iroquois, Kankakee, Will, Cook, Lake
Highway system
	United States Numbered Highway System; List; Special; Divided; Illinois State Highway System; Interstate; US; State; Tollways; Scenic;

U.S. Route 45 (US 45) in the state of Illinois is a major north–south U.S. Highway that runs from the Brookport Bridge over the Ohio River at Brookport north through rural sections of eastern Illinois and then through the suburbs of Chicago to the Wisconsin state line east of Antioch. This is a distance of 428.99 miles (690.39 km). US 45 is the longest numbered route in Illinois.