U.S. Route 76 in South Carolina

U.S. Highway 76
U.S. Highway 76
	Route of US 76 in South Carolina highlighted in red
Route information
	Maintained by SCDOT
Length	297.9 mi (479.4 km)
Existed	1926–present
Major junctions
West end	US 76 / SR 2 at the Georgia state line near Clayton
	I-85 near Anderson; I-26 / US 176 in Irmo; I-20 on the Seven Oaks–St. Andrews city line; I-26 / I-126 near West Columbia; US 1 / US 378 in Columbia; US 15 / US 401 / US 378 / US 521 in Sumter; I-95 near Florence;
East end	US 76 at the North Carolina state line near Fair Bluff, NC
Location
Country	United States
State	South Carolina
Counties	Oconee, Pickens, Anderson, Greenville, Laurens, Newberry, Richland, Lexington, Sumter, Lee, Florence, Marion, Horry
Highway system
	United States Numbered Highway System; List; Special; Divided; South Carolina State Highway System; Interstate; US; State; Scenic;

U.S. Route 76 (US 76) is an east–west U.S. highway in the U.S. state of South Carolina. Being one of the longest and most important highways in the state, it connects the cities of Anderson, Columbia, Sumter and Florence.