WBP1

WBP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1JMQ, 1K5R
Identifiers
Aliases	WBP1, WBP-1, WW domain binding protein 1
External IDs	OMIM: 606961; MGI: 104710; HomoloGene: 8267; GeneCards: WBP1; OMA:WBP1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	74,460,891 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	83,098,540 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; pituitary gland; ; Amygdala; ; nucleus accumbens; ; anterior pituitary; ; putamen; ; caudate nucleus; ; right adrenal cortex; ; hippocampus proper; ; left lobe of thyroid gland;
	Top expressed in
	choroid plexus of fourth ventricle; ; external carotid artery; ; ventricular zone; ; internal carotid artery; ; vestibular sensory epithelium; ; ganglionic eminence; ; neural tube; ; medial ganglionic eminence; ; neural layer of retina; ; maxillary prominence;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; WW domain binding;
Cellular component	cellular component;
Biological process	biological process;
	Sources:Amigo / QuickGO
Orthologs
	23559
	22377
	ENSG00000239779
	ENSMUSG00000030035
	Q96G27
	P97764
	NM_012477
	NM_001083922; NM_001083923; NM_016757
	NP_036609
	NP_001077391; NP_001077392; NP_058037
	Wikidata
View/Edit Human	View/Edit Mouse

WW domain-binding protein 1 is a protein that in humans is encoded by the WBP1 gene.

The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands.

This gene encodes a WW domain binding protein, which binds to the WW domain of Yes kinase-associated protein by a conserved region: XPPXY motif. The function of this protein has not been determined.