WDFY3

WDFY3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3WIM
Identifiers
Aliases	WDFY3, ALFY, ZFYVE25, WD repeat and FYVE domain containing 3, BCHS, MCPH18
External IDs	OMIM: 617485; MGI: 1096875; HomoloGene: 22855; GeneCards: WDFY3; OMA:WDFY3 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	84,966,690 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	102,217,787 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; Achilles tendon; ; corpus callosum; ; inferior olivary nucleus; ; dorsal motor nucleus of vagus nerve; ; ventricular zone; ; internal globus pallidus; ; ganglionic eminence; ; epithelium of colon; ; optic nerve;
	Top expressed in
	mammillary body; ; lateral hypothalamus; ; lateral septal nucleus; ; lobe of cerebellum; ; lateral geniculate nucleus; ; cerebellar vermis; ; dorsal tegmental nucleus; ; ventromedial nucleus; ; paraventricular nucleus of hypothalamus; ; medial dorsal nucleus;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; 1-phosphatidylinositol binding; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; metal ion binding; lipid binding;
Cellular component	Atg12-Atg5-Atg16 complex; PML body; nuclear membrane; nuclear envelope; extrinsic component of membrane; extrinsic component of autophagosome membrane; autophagosome; cytoplasm; inclusion body; membrane; nucleus; nucleolus; plasma membrane; cytosol; axon; cell projection; perikaryon;
Biological process	aggrephagy; autophagy; multicellular organism development;
	Sources:Amigo / QuickGO
Orthologs
	23001
	72145
	ENSG00000163625
	ENSMUSG00000043940
	Q8IZQ1
	Q6VNB8
	NM_014991; NM_178583; NM_178585
	NM_172882; NM_028124
	NP_055806
	NP_766470
	Wikidata
View/Edit Human	View/Edit Mouse

WD repeat and FYVE domain-containing protein 3 is a protein that in humans is encoded by the WDFY3 gene.

This gene encodes a protein which contains WD repeats and an FYVE domain. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.