XCR1

XCR1
Identifiers
Aliases	XCR1, CCGPR5, X-C motif chemokine receptor 1
External IDs	OMIM: 600552; MGI: 1346338; HomoloGene: 21095; GeneCards: XCR1; OMA:XCR1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	46,085,825 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	123,691,094 bp
RNA expression pattern
	Top expressed in
	gonad; ; testicle; ; lymph node; ; appendix; ; pancreatic ductal cell; ; gallbladder; ; skin of leg; ; skin of abdomen; ; decidua; ; mucosa of transverse colon;
	Top expressed in
	morula; ; embryo; ; thymus; ; mesenteric lymph nodes; ; spleen; ; blastocyst; ; meninges; ; right kidney; ; duodenum; ; jejunum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; chemokine receptor activity; signal transducer activity; C-C chemokine receptor activity; chemokine binding; C-C chemokine binding;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane; external side of plasma membrane;
Biological process	positive regulation of cytosolic calcium ion concentration; chemotaxis; G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; inflammatory response; signal transduction; chemokine-mediated signaling pathway; immune response; calcium-mediated signaling; cell chemotaxis;
	Sources:Amigo / QuickGO
Orthologs
	2829
	23832
	ENSG00000173578
	ENSMUSG00000060509
	P46094
	Q9R0M1
	NM_005283; NM_001024644; NM_001381860
	NM_011798
	NP_001019815; NP_005274; NP_001368789
	NP_035928
	Wikidata
View/Edit Human	View/Edit Mouse

The "C" sub-family of chemokine receptors contains only one member: XCR1, the receptor for XCL1 and XCL2 (or lymphotactin-1 and -2).

XCR1 is also known as GPR5.