Zofenopril

Zofenopril
Clinical data
Trade names	Zocardis (RU)
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	C09AA15 (WHO) ;
Identifiers
	IUPAC name (2S,4S)-1-[(2S)-3-benzoylsulfanyl-2-methylpropanoyl]-4-phenylsulfanylpyrrolidine-2-carboxylic acid;
CAS Number	81872-10-8 ;
PubChem CID	92400;
IUPHAR/BPS	6462;
DrugBank	DB13166 ;
ChemSpider	83422 ;
UNII	290ZY759PI;
KEGG	D08688 ;
ChEBI	CHEBI:78539 ;
ChEMBL	ChEMBL331378 ;
CompTox Dashboard (EPA)	DTXSID0046640 ;
Chemical and physical data
Formula	C22H23NO4S2
Molar mass	429.55 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N2[C@H](C(=O)O)C[C@H](Sc1ccccc1)C2)[C@H](C)CSC(=O)c3ccccc3;
	InChI InChI=1S/C22H23NO4S2/c1-15(14-28-22(27)16-8-4-2-5-9-16)20(24)23-13-18(12-19(23)21(25)26)29-17-10-6-3-7-11-17/h2-11,15,18-19H,12-14H2,1H3,(H,25,26)/t15-,18+,19+/m1/s1 ; Key:IAIDUHCBNLFXEF-MNEFBYGVSA-N ;
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Zofenopril (INN) is a medication that protects the heart and helps reduce high blood pressure. It is an angiotensin-converting enzyme (ACE) inhibitor.

In small studies, zofenopril appeared significantly more effective in reducing hypertension than two older antihypertensive drugs, atenolol and enalapril, and was associated with fewer adverse effects.

It was patented in 1978 and approved for medical use in 2000.