Antoinette of Bourbon
| Antoinette de Bourbon | |
|---|---|
| Duchess of Guise | |
Portrait by Léonard Limousin | |
| Born | 25 December 1494 Chateau de Ham, Somme department, Picardy, France |
| Died | 22 January 1583 (aged 88) Chateau de Joinville |
| Spouse | |
| Issue |
|
| House | Bourbon |
| Father | Francis, Count of Vendôme |
| Mother | Marie I, Countess of Saint-Pol |
Antoinette of Bourbon, Duchess of Guise (25 December 1494 – 22 January 1583), was a French noblewoman of the House of Bourbon. She was the wife of Claude of Lorraine, Duke of Guise.