SNX6
| sorting nexin 6 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SNX6 | ||||||
| NCBI gene | 58533 | ||||||
| HGNC | 14970 | ||||||
| OMIM | 606098 | ||||||
| RefSeq | NM_021249 | ||||||
| UniProt | Q9UNH7 | ||||||
| Other data | |||||||
| Locus | Chr. 14 q13 | ||||||
| |||||||
Sorting Nexin 6 also known as SNX6 is a well-conserved membrane-associated protein belonging to the sorting nexin family that is a component of the retromer complex. The protein contains a coiled-coil domain at its C terminus and a PX domain at its N terminus. Binding to PIM1 causes translocation to the nucleus. SNX6 has been shown to associate with TRAF4.