U.S. Route 412

U.S. Route 412
U.S. Route 412
	US 412 highlighted in red
Route information
Length	1,130 mi (1,820 km)
Existed	1982 (extended east in 1984, 1989, west in 1989, 1994)–present
Major junctions
West end	US 56 / NM 21 at Springer, NM
	I-35 near Enid, OK; I-44 at Tulsa, OK; I-49 / US 62 / US 71 at Springdale, AR; I-55 / US 61 at Hayti, MO; I-155 / US 51 at Dyersburg, TN; I-40 at Jackson, TN;
East end	I-65 at Columbia, TN
Location
Country	United States
States	New Mexico, Oklahoma, Arkansas, Missouri, Tennessee
Highway system
	United States Numbered Highway System; List; Special; Divided;

U.S. Route 412 is an east–west United States highway, first commissioned in 1982. U.S. 412 overlaps expressway-grade Cimarron Turnpike from Tulsa west to Interstate 35 and the Cherokee Turnpike from 5 miles (8.0 km) east of Chouteau, Oklahoma, to 8 miles (13 km) west of the Arkansas state line. It runs the entire length of the Oklahoma Panhandle and traverses the Missouri Bootheel.

As of 2020, the highway's eastern terminus is in Columbia, Tennessee at an intersection with Interstate 65, where it continues east as State Route 99. Its western terminus is in Springer, New Mexico at an intersection with Interstate 25.