This article is about the section of U.S. Route 412 in Arkansas. For the entire route, see 
U.S. Route 412.
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| US 412 highlighted in red | 
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| Maintained by ArDOT | 
| Length | 290 mi (470 km) | 
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| Existed | 1988 (1988)–present | 
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| West end | US 412 at the Oklahoma state line | 
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| Major intersections |  | 
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| East end | US 412 at the Missouri state line | 
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| Country | United States | 
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| State | Arkansas | 
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| Counties | Benton, Washington, Madison, Carroll, Boone, Marion, Baxter, Fulton, Sharp, Lawrence, Randolph, Greene | 
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U.S. Highway 412 (US 412) runs east-to-west through northern Arkansas for about 290 miles (470 km). The route begins at the Oklahoma state line near Siloam Springs, and ends at the Missouri state line east of Paragould.